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RU486和ONO802阴道栓终止早孕的临床观察
引用本文:朱桂金,罗丽兰,张先柔.RU486和ONO802阴道栓终止早孕的临床观察[J].华中科技大学学报(医学版),1992(2).
作者姓名:朱桂金  罗丽兰  张先柔
作者单位:同济医科大学附属同济医院妇产科 (朱桂金,罗丽兰),同济医科大学附属同济医院妇产科(张先柔)
摘    要:本文观察了42例联合使用RU486和前列腺素ONO802阴道栓终止49d以内早孕的效果。联合用药完全流产率为90.2%,不完全流产率为4.9%,失败率为4.9%。平均流产时间为服药后84h,出血持续时间为13d,月经恢复时问为31d。结果表明,RU486和ONO802合用是一种安全。简便,有效的终止早孕的新方法。

关 键 词:RU486  ONO802  流产  人工

Termination of Early Pregnancy with RU486 and ONO802
Zhu Guijin,Luo Lilan,Zhang Xianrou.Termination of Early Pregnancy with RU486 and ONO802[J].Journal of Huazhong University of Science and Technology(Health Sciences),1992(2).
Authors:Zhu Guijin  Luo Lilan  Zhang Xianrou
Institution:Zhu Guijin,Luo Lilan,Zhang XianrouDepartment of Obstetrics and Gynecology,Tongji Hospital,Tongji Medical University,Wuhan
Abstract:The efficacy and acceptability of an antiprogestin RU486 used in combination with the vaginal prostaglandin analogue ONO802 for termination of early pregnancy were assessed in 42 women with 49 day gestation. The assessment was performed under the auspices of the World Health Organnization. The results showed that the frequency of complete and incomplete abortion was 90 % and 5 %, respectively with a failure rate of 5%. The abortion occurred 64 h after start of therapy. The mean duration of bleeding was approximately 13 days. The mean time from abortion to the start of the first menstruation was 31 days. No serious complications or side effects were observed. Thus it may be concluded that the combination regimen of RU486 and prostaglandin is a safe, simple and effective method for medical termination of early pregnancy.
Keywords:RU486  ONO802  abortion  induced
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