急性肾衰竭患者血清胆碱酯酶变化的意义

目的通过观察急性肾衰竭（ARF）患者血清胆碱酯酶（CHE）的变化，探讨血清CHE与ARF预后的关系，并分析其临床意义。方法将68例ARF患者分为存活组（A组）及死亡组（B组），检测其治疗前后血清CHE，并与40例肾功能正常的原发肾小球疾病患者（M组）和30例健康体检者（N组）比较。结果A组和B组患者血清CHE均较M组和N组降低；而M组与N组间无显著性差异；A组患者治疗后血清CHE恢复，与治疗前CHE相比差异有统计学意义；B组患者治疗后血清CHE持续降低。结论血清CHE可作为ARF的检测物之一，对ARF患者的病情监测和预后判断具有重要的临床意义。

The alternation and significance of cholinesterase in patients with acute renal failure

Objective To study the alternation and significance of serum cholinesterase（CHE） in patients with acute renal failure（ARF）. Methods CHE were detected before and after treatment in 68 patients with ARF,and the 40 primary glomerular diseases patients with normal renal function and 30 healthy patients were as control groups. Results CHE in patients with ARF were much lower than those in the control groups. After treatment, CHE had increased in the survival group, but decreased in the death group. Conclusions CHE could be as the marker of ARF, it had significantly clinical value on monitoring disease progression and evaluating prognosis in ARF.