| 复圣散抗脑缺血再灌注损伤的机理研究 |
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| 引用本文： | 王蕴红,马贵宝,王燕萍,李澎,贾旭,严京,黄启福. 复圣散抗脑缺血再灌注损伤的机理研究[J]. 北京中医药大学学报, 2001, 24(4): 20-22,44 |
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| 作者姓名： | 王蕴红 马贵宝 王燕萍 李澎 贾旭 严京 黄启福 |
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| 作者单位： | 1. 北京中医药大学
2. 山西太原康复医院 |
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| 基金项目： | 中国博士后基金课题 (No .0 5 43 2 ) |
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| 摘 要： | 以大鼠缺血再灌注损伤为模型 ,采用放免测定及原位杂交等方法 ,观察复圣散对大鼠缺血再灌注损伤起到保护作用的机理。结果提示大鼠缺血再灌注后 ,cNOSmRNA、ETmRNA高表达引起NOS、ET含量增高 ,复圣散能够降低NOS、ET含量起到保护作用
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| 关 键 词： | 复圣散 脑缺血 一氧化氮 内皮素 大鼠 |
| 修稿时间： | 2000-12-18 |
Study on the Mechanism of the Effects of Fusheng Powder Against the Lesions due to Cerebral Ischemia and Reperfusion |
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| Wang Yunhong,Ma Guibao,Wang Yanping,et al.. Study on the Mechanism of the Effects of Fusheng Powder Against the Lesions due to Cerebral Ischemia and Reperfusion[J]. Journal of Beijing University of Traditional Chinese Medicine, 2001, 24(4): 20-22,44 |
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| Authors: | Wang Yunhong Ma Guibao Wang Yanping et al. |
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| Abstract: | The mechanism of the protective effects of Fusheng Powder against the lesions due to cerebral ischemia and reperfusion was studied in rats by radioimmunoassay and the in situ hybridization technique. It was found that the overdue expressions of cNOS mRNA and ET mRNA could increase the levels of NOS and ET, and Fusheng Powder could decrease the levels of NOS and ET and exert protective effects against the lesions due to cerebral ischemia and reperfusion. |
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| Keywords: | Cerebral Ischemia Fusheng Powder Nitric Oxide Endothelin Rat |
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