双眼先天性白内障儿童生活质量量表的制订及评价

目的制订8～15岁双眼先天性白内障儿童生活质量量表,评价量表的效度、信度以及反应度。方法根据儿童生活质量的定义设计,涵盖与视功能损害有关的重要指标,编制23个条目的双眼先天性白内障儿童生活质量量表。应用该量表对8～15岁的18例正常视力儿童和76例双眼先天性白内障儿童进行了量表调查。应用离散程度法、相关系数法、因子分析法、区分度分析法、克朗巴赫系数法和重测信度法来筛选量表有效条目,并评价筛选后量表的效度、信度以及反应度。结果条目5、7和21经筛选后删除,形成20个条目的量表。每个条目和每个分项的内容效度相关系数均大于0．6（P〈0．05）。正常儿童和白内障儿童、白内障儿童术前和术后总得分间的差异均有统计学意义（P=0．000）。重测信度的相关系数为0．895（P=0．000）。本量表4个分项的克朗巴赫a信度系数值分别为0．822、0．922、0．797和0．794。效应尺度统计量为1．141。结论经筛选后的20个条目的量表符合生活质量量表效度、信度以及反应度的技术要求,可以应用于8～15岁的双眼先天性白内障儿童生活质量的临床研究。

Development and evaluation of the scale of quality of life for children with bilateral congenital cataract

OBJECTIVE: To develop and evaluate the 23-item quality of life (QoL) 125 scale contained four subscales for children with bilateral congenital cataract. METHODS: 18 children with normal visual acuity and 76 patients with congenital bilateral cataract (age range of 8 years to 15 years) were evaluated with QoL. The 23-item QoL scale contained the following subscales: visual function, self-care, sociality, and mentality. Dispersion, correlation coefficient, factor analysis, discrimination analysis, Chronbach alpha and test-retest reliability were applied to select the parameters and data analysis. RESULTS: The new scale included 20 items after screening. The correlation coefficients of content validity of each item and subscale were beyond 0.6 (P < 0.05). Statistically significant difference was found at discrimination analysis between normal and cataract children (P' = 0.000), the differences was also demonstrated between preoperative and postoperative cataract children (P' = 0.000). The coefficient of test-retest reliability was 0.895 (P = 0.000), and the Chronbach's alpha coefficients of four subscales were 0.822, 0.922, 0.797, and 0.794 respectively. The statistics value of effective size was 1.141. CONCLUSIONS: significant reliability, validity and responsibility to change life quality were achieved in the 20-item scale of QoL for children with bilateral congenital cataract. This scale can be applied to evaluate the life quality of bilateral cataract children.