吉林省长春市双阳区齐家乡原发性闭角青光眼的患病率调查及其影响因素

目的研究吉林省长春市农村人口原发性闭角型青光眼（PACG）的患病率及其相关影响因素。方法2004年9月至2005年2月,对长春市双阳区齐家乡两个自然村的40岁及以上人群共1139人进行青光眼调查。现场检查项目包括常规视力、裂隙灯显微镜、周边前房深度、眼压及眼底检查。对可疑青光眼患者进一步详细检查眼压、前房角镜、眼底及视野。结果实际检查人数为1139人,受检率为74．5％;确诊为PACG者29例,青光眼患病率为2．5％,随年龄增加其患病率增高。其中男性青光眼患病率为1．5％,女性为3．5％;女性青光眼患病率明显高于男性。周边前房深度检查发现女性人群浅前房的比例明显高于男性,且随年龄的增加浅前房的比例明显增大。有青光眼家族史的人群中,PACG的患病率高于无青光眼家族史的人群。结论长春市双阳区PACG的患病率较高,其患病率与患者性别、年龄、家族史及周边前房深度等因素有关.

The prevalence of primary angle-closure glaucoma and its causes in rural area of Shuangyang district in Changchun, Jilin province

OBJECTIVE: To investigate the prevalence of primary angle-closure glaucoma (PACG) and its causes in a rural area in Changchun, China. METHODS: From the rural area of Qijiaxiang, Shuangyang district of Changchun, 1139 individuals aged 40 years and above were randomly selected for the study from September 2004 to February 2005 using Zhao Jialiang's standard. All subjects in this study underwent a preliminary screening examination including visual acuity, the peripheral depth of anterior chamber, slit lamp, tonometry and fundus. The suspects of PACG were asked to repeat the following examinations: tonometry, gonioscopy, fundus, and visual field assessment. RESULTS: 1139 of 1528 subjects were invited to participate in the study (response rate 74.5%). In those age 40 years and above, the prevalence of PACG was 1.5% in men, 3.5% in women, and 2.5% in general population, respectively. The prevalence was increased with age. The anterior chamber was significantly (P<0.01) narrower in the female group than in the male group when the peripheral depth of anterior chamber was compared. The prevalence of PACG was significantly (P<0.02) higher in subjects with positive family history than with negative family history. CONCLUSIONS: In the rural area in Shuangyang district of Changchun, the prevalence of PACG is higher than other regions surveyed in China. Sex, age, family history and the peripheral depth of anterior chamber are significant risk factors in PACG.