The implications of a growing evidence base for drug use in elderly patients. Part 3. Beta-adrenoceptor blockers in heart failure and thrombolytics in acute myocardial infarction |
| |
| Authors: | Mangoni A A Jackson S H D |
| |
| Affiliation: | Department of Clinical Pharmacology and Centre for Neuroscience, Flinders University, Adelaide, Australia. arduino.mangoni@flinders.edu.au |
| |
| Abstract: | Beta-adrenoceptor blockers and thrombolytic agents are of established value in the pharmacological management of heart failure and ST-elevation myocardial infarction, respectively. However, there is uncertainty as to whether these therapeutic strategies can be safely and effectively adopted in elderly patients with comorbidities, particularly in old-old individuals. This review focuses on these trials and the age-related efficacy and safety of these drugs. |
| |
| Keywords: | congestive cardiac failure elderly patients myocardial infarction randomized controlled trials thrombolytic agents β-adrenoceptor blockers |
| 本文献已被 PubMed 等数据库收录！ |
