| Abstract: | The enzyme L-gulonolactone oxidase can catalyze the conversion of the semicarbazone of D-glucuronolactone to the semicarbazone of L-ascorbic acid, which will react as ascorbic acid in identification tests based on iron reduction. This observation explains earlier speculations that a microsomal enzyme converting D-glucuronolactone to L-gulonolactone was potentially important in L-ascorbic acid synthesis. In the catabolism of ascorbic acid, oxidation at C-6 appears to be a major process in monkeys. |
