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IgE Synthesis in vitro: Attempt to Isolate Stimulating Factors
Authors:B. De  La Parra   N. Vulliet   J.-P. Girard
Affiliation:Division of Immunology and Allergology, Geneva University, Medical School, Geneva, Switzerland
Abstract:Studies made in our laboratory have demonstrated the presence in atopic serum of enhancing factors(s) for in vitro IgE synthesis by peripheral blood lymphocytes (BPL). Here we show that these enhancing factors can be recovered from human serum by means of immunoabsorbents. This factor is able to stimulate in vitro IgE synthesis by PBL independent of presence of IgE.
Keywords:allergy    atopy    IgE    IgE enhancing factors    in vitro IgE synthesis
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