| RP-HPLC测定保精颗粒中五味子醇甲的含量 |
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| 引用本文： | 唐晓霞,陈丽,苏万福. RP-HPLC测定保精颗粒中五味子醇甲的含量[J]. 中国药物警戒, 2013, 10(9): 543-544 |
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| 作者姓名： | 唐晓霞 陈丽 苏万福 |
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| 作者单位： | 济川药业集团股份有限公司,江苏泰兴,225441 |
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| 摘 要： | 目的 建立保精颗粒中五味子醇甲的含量测定方法.方法 采用高效液相色谱法,Kromasil C18(250 mm×4.6 mm,5μm)色谱柱,流动相为乙腈-水(45∶55),流速1.0 mL· min-1,检测波长250 nm.结果 方法学考察结果表明,五味子醇甲平均加样回收率为100.7％(RSD=1.3％,n=6).结论 该方法专属性强、重复性好,可作为保精颗粒的质量控制方法.
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| 关 键 词： | 保精颗粒 五味子醇甲 RP-HPLC 含量测定 |
A Method for Quantitative Determination of Schisandrim in Baojing Granule by RP-HPLC |
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| TANG Xiao-xia , CHEN Li , SU Wan-fu. A Method for Quantitative Determination of Schisandrim in Baojing Granule by RP-HPLC[J]. Chinese JOurnal of Pharmacovigilance, 2013, 10(9): 543-544 |
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| Authors: | TANG Xiao-xia CHEN Li SU Wan-fu |
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| Affiliation: | (Jumpcan Pharmaceutical Group Limited by Share, Jiangsu Taixing 225441, China) |
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| Abstract: | Objective To establish a method for quantitative determination of schisandrin in baojing granule. Methods HPLC was used. The samples were separated on a kromasil C18 column（250mm×4.6mm, 5μm） with a mobile phase of acetonitrile and water（45：55v/v）, pumped at the flow rate of 1.0 mL·min-1 and detected at 250 nm. Results The result showed that the average recovery of schisandrin was 100.7%（RSD=l.3%, n=6）. Conclusion The method has a good specificity and stability, which can be applied to the quality control of baojing granule. |
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| Keywords: | baojing granule schisandrin RP-HPLC assaying |
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