超声心动图对高血压病人左室舒张功能再评价

目的 探讨超声心动图对高血压（EH）病人左室舒张功能评价价值。方法 140例EH病人分为左室肥厚组47例，非左室肥厚组93例，予二维超声心动图及Doppler频谱检测，并与25例正常人对照。结果 在正常组和NLVH组，E/A比值、PA值和PAi有显著差异；IVRT、LAD在3组之间有显著差异；EF%值在NLVH组与正常组相似，与LVH组差异有统计学意义。结论 PA、PAi增高、E/A比值减低、IVRT延长和LAD增大是EH左室舒张功能减低的敏感指标。EF值变化提示EH早期左室收缩功能并未受到影响，随着疾病进展而逐步受损。

Reevaluation of LeftVentricular Diastolic Function in Essential Hypertension Patients by Echocardiography

Purpose To assess left ventricular diastolic function in the patients with essentialhypertension. Methods 25 normotensives,93 hypertensiives without hypertrophy (NLVH) and 47 withhypertrophy (LVH)(LVMI, left ventricular mass index ＞ 124 g/m2 in males and 110 g/m2 in females)underwent 2DE and Doppler echocardiography. Results The ratio of early to late peak velocity (E/A)was 1.21 ± 0.24 in normotensives and 1.03 ± 0.23 in NLVH patients( P ＜ 0.01 ); reversed pulmonaryvenous flow at atrial systole PA wave was (32.7 ± 7.5 ) vs (38.9 ± 8.7) cm/s (P ＜ 0.01 ) in normotensivesand in NLVH patients respectively. The isovolumic relaxation time (IVRT) and left atrial dimension (LAD)have significant differences in three groups ( P ＜ 0. 05 - 0. 001 ). EF value was similar betweennormotensives and NLVH patients, but it was lower in LVH patients ( P ＜ 0.01 ). Conclusions E/Aratio, PA wawe, Pai, IVRT and LAD are sensitive parameters indicating mild diastolic left ventriculardysfunction. Systolic left ventricular function has no change in NLVH patients.