放射性核素动态显像在小儿先天性肥厚性幽门狭窄中的临床应用价值

目的:评价放射性核素动态显像在小儿先天性肥厚性幽门狭窄中的临床应用价值。方法:将对照组、病例组、手术组患儿进行放射性核素液体胃排空动态显像,对所有图像进行反流及其持续时间的观察,定量计算反流率、胃排空率和半排时间。结果:病例组反流率、反流持续时间均高于对照组,手术组反流率和反流持续时间均较病例组降低;与对照组比较,病例组胃排空率明显降低(P<0.05),半排时间延长(P<0.05);与病例组比较,手术组胃排空率升高(P<0.05),其半排时间缩短(P<0.05),而手术组与对照组比较,胃排空率和半排时间差异无显著性(P>0.05)。结论:放射性核素动态胃排空显像是动态、定量评价小儿先天性肥厚性幽门狭窄胃排空能力、反流状况及其治疗效果的一项重要的无创性检测手段。

Clinical value of radionuclide dynamic imaging in infants with congenital hypertrophic pyloric stenosis

Objective:To evaluate the clinical value of radionuclide dynamic imaging in infants with congenital hypertrophic pyloric stenosis. Methods:The gastric emptying dynamic imaging with radionuclide liquid was performed in infants who divided into normal control group,case group,and surgery group. The reflux and its duration were observed,and the percent of reflux,gastric emptying rate,and gastric emptying half-time were determined. Results:Compared with normal control group,in case group,the percent of reflux and the duration of reflux were significantly higher;the gastric emptying rate was significantly lower;the gastric emptying half-time was significantly longer (all P < 0.05). Compared with case group,in surgery group,the percent of reflux and the duration of reflux were significantly lower,and the gastric emptying rate and gastric emptying half-time were significantly improved (all P < 0.05). No significant difference in gastric emptying rate and gastric emptying half-time was found between normal control group and surgery group. Conclusion:The gastric emptying dynamic imaging with radionuclide liquid is an important approach to evaluating the ability of gastric emptying,the state of reflux,and the therapeutic outcome in infants with congenital hypertrophic pyloric stenosis.