| 小鼠不同锌营养状态对胸腺(九)肽的影响 |
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| 引用本文： | 陈竞,曲宁,夏弈明. 小鼠不同锌营养状态对胸腺(九)肽的影响[J]. 卫生研究, 2005, 34(4): 430-432 |
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| 作者姓名： | 陈竞 曲宁 夏弈明 |
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| 作者单位： | 中国疾病预防控制中心营养与食品安全所,北京,100050 |
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| 摘 要： | 目的观察小鼠不同锌营养状态对胸腺(九)肽的影响。方法在锌耗竭期,分低锌组(DC)(饲料含锌5.2mgkg)、对饲组(PZ)和正常锌组(饲料含锌25.6mgkg)。继后的锌补充期,分低锌组(DC)、低锌正常组(DZNZ)和对饲自由组(PZNZ)。动态观察血锌含量和胸腺(九)肽的含量。结果在血锌未发生明显变化时,胸腺(九)肽含量即随锌的耗竭而迅速下降,又伴随锌的补充而快速上升。结论胸腺(九)肽是锌营养状态变化的敏感指标。
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| 关 键 词： | 锌 胸腺(九)肽 |
| 文章编号： | 1000-8020(2005)04-0430-03 |
| 修稿时间： | 2004-08-26 |
Effect of zinc on thymulin level in mice |
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| Chen Jing,QU Ning,Xia Yi-ming. Effect of zinc on thymulin level in mice[J]. Journal of hygiene research, 2005, 34(4): 430-432 |
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| Authors: | Chen Jing QU Ning Xia Yi-ming |
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| Affiliation: | Institute of Nutrition and Food Safety, Chinese Center for Disease Control and Prevention, Beijing 100050, China. |
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| Abstract: | Objective In order to investigate the roles of the different levels of zinc nutrition status on the thymulin of the mice. Methods The experiment included two periods: zinc depleted period and repletion period. In the depleted period, mice were divided into 3 dose groups: zinc deficient group ~ZD, 5.2mg/kg), zinc pair-fed group ~PZ) and normal zinc group~NZ,25.6mg/kg). In the repletion period, mice were divided into 3 dose groups: ZD group, DZ-NZ group and PZ-NZ group.Results The results showed that a signification decrease of thymulin level was observed as a result of zinc deficiency and was increased rapidly follow zinc supplement, while the plasma zinc was kept the same level.Conclusion The thymulin is a sensitive biomarker for assess the zinc status. |
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| Keywords: | zinc thymulin |
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