| 肝精补血素口服液的药效学研究 |
| |
| 引用本文： | 袁卫梅,吴生谦.肝精补血素口服液的药效学研究[J].中国药业,2006,15(17):29-30. |
| |
| 作者姓名： | 袁卫梅 吴生谦 |
| |
| 作者单位： | 1. 河南省新乡市药品检验所,河南,新乡,453000
2. 新乡同心药业有限公司,河南,新乡,453000 |
| |
| 摘 要： | 目的验证肝精补血素口服液的药效。方法建立血虚模型，测定小鼠、大鼠失血前、失血24h及灌胃给药后的RBC，Hb，吞噬功能和游泳时间。结果低剂量（19．4g／kg）和高剂量（38．9g／kg）的肝精补血素口服液均能明显增加失血性贫血小鼠的RBC和Hb，提高贫血小鼠的非特异免疫功能，提高小鼠的耐受力，延长小鼠的游泳时间；对失血性血虚模型大鼠，剂量分别为15．6g／kg和31．1g／kg的肝精补血素口服液也能显著升高RBC和Hb。结论肝精补血素口服液能明显提高贫血动物的RBC和Hb，并有提高免疫力及抗疲劳作用。
|
| 关 键 词： | 肝精补血素口服液 药效学 实验研究 |
| 文章编号： | 1006-4931(2006)17-0029-02 |
| 收稿时间： | 03 6 2006 12:00AM |
| 修稿时间： | 04 18 2006 12:00AM |
Study on Pharmacodynamics of Ganjing Buxuesu Oral Liquid |
| |
| Yuan Weimei,Wu Shengqian.Study on Pharmacodynamics of Ganjing Buxuesu Oral Liquid[J].China Pharmaceuticals,2006,15(17):29-30. |
| |
| Authors: | Yuan Weimei Wu Shengqian |
| |
| Institution: | 1, Xinxiang Institute for Drug Control of Henan Province, Xinxiang, Henan, China 453000; 2, Xinxiang Tongxin Pharmaceutical Co,, Ltd,, Xinxiang, Henan, China 453000 |
| |
| Abstract: | Objective To establish the pharmacodynamics of Ganjing Buxuesu oral liquid. Methods By establishing the blood-deficiency model in mice and rats,to determine RBC,Hb,the swimming time around losing blood. Results Ganjing Buxuesu oral liquid could significantly increase the quantities of RBC and hemoglobin in rats and mice models with blood- deficiency anemia, increase the non- special immune function and tolerance of anemia mice,and lengthen the swimming time. At the dosage of 19. 4, 38.9 g/kg, Ganjing Buxuesu oral liquid could significantly increase the quantities of RBC and Hb in rats and mice models with hemorrhagic blood- deficiency. Conclusion Ganjing Buxuesu oral liquid can obviously increase the quantities of RBC,Hb and inmmunity of anemia animals,and have anti-weary function. |
| |
| Keywords: | Ganjing Buxuesu oral liquid pharmacodynamics experimental study |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
