Nosocomial post-traumatic Rhizomucor soft tissue and bone infection treated with liposomial amphotericin B: case report |
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Authors: | M. B. Pasticci F. Baldelli C. Fiacca G. Giustelli L. M. Lapalorcia S. Morosi G. Stagni |
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Affiliation: | (1) Infectious Disease Section Department of Experimental Medicine and Biochemical Sciences, University of Perugia, I-06100 Perugia, Italy;(2) Department of Surgical Sciences Orthopaedics Section, University of Perugia, Perugia, Italy |
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Abstract: | Mucornycosis is a rare fungal infection most commonly occuring in patients with severe immunocompromise, diabetes, uremia or trauma. Only a few cases of non axial skeletal bone osteomyelitis have been reported. We report a case of nosocomial cellulitis and osteomyelitis complicating a posttraumatic bacterial infection, successfully treated with liposomial amphotericin B and surgical debridement. Traumatized patients with extensive tissue loss, receiving broad-spectrum antibiotics, can develop impaired immune responses and are at risk for fungal infections. |
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Keywords: | Nosocomial cellulitis and osteomyelitis Rhizomucor |
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