| 新疆雪莲的香豆素类化学成分的研究 |
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| 引用本文： | 杨峻山,谢凤指,刘庆华,吴霞.新疆雪莲的香豆素类化学成分的研究[J].中国药学杂志,2006,41(23):1774-1776. |
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| 作者姓名： | 杨峻山 谢凤指 刘庆华 吴霞 |
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| 作者单位： | 1. 中国医学科学院-中国协和医科大学药用植物研究所,北京,100094
2. 新疆维吾尔自治区药物研究所,乌鲁木齐,800007 |
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| 摘 要： | 目的研究新疆雪莲(Saussurea involucrate Kar.et Kir)的化学成分。方法应用各种柱色谱的方法进行分离;应用化学和各种光谱分析的方法鉴定化合物。结果从新疆雪莲的乙醇提取物的乙酸乙酯萃取物中分离得到8个香豆素类成分,它们分别为蛇床子内酯(osthol),佛手内酯(bergapten),异茴芹内酯(isopimpinellin),爱得尔庭(edultin),叶鞘二醇二乙酸酯(vaginidiol di-acetate),别异因波拉托内酯(alloisoimperatorin),噢洛内酯(oroselol),花椒香豆素(xanthotoxol)。结论这8个香豆素均为首次从新疆雪莲中分离得到。
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| 关 键 词： | 新疆雪莲 化学成分 |
| 文章编号： | 1001-2494（2006）23-1774-03 |
| 收稿时间： | 2006-03-30 |
| 修稿时间： | 2006-03-30 |
Studies on Coumarins of Saussurea involucrate Kar. et Kir |
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| YANG Jun-shan,XIE Feng-zhi,LIU Qing-hua,WU Xia.Studies on Coumarins of Saussurea involucrate Kar. et Kir[J].Chinese Pharmaceutical Journal,2006,41(23):1774-1776. |
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| Authors: | YANG Jun-shan XIE Feng-zhi LIU Qing-hua WU Xia |
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| Institution: | 1.Institute of Medicinal Plant Development, Chinese Academy Medical Sciences & Peking Union Medical College, Beijing 100094，China；2.Xinjiang Institute of Marteria Medica, Wulumuqi 800007，China |
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| Abstract: | OBJECTIVE To study the chemical constituents of Saussurea involucrate Kar. et Kir. METHODS The chemical constituents were isolated by column chromatography, and their structures were elucidated by chemical and spectroscopy evidences.RESULTS Eight coumarin compounds were isolated and identified as osthol, bergapten, isopimpinellin, edultin, vaginidiol diacetate, alloisoimperatofin, oroselol, xanthotoxol, respectively. CONCLUSION The eight coumarin compounds are isolated from Saussurea involucrate Kar. et Kit. for the first time. |
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| Keywords: | Saussurea involucrate Kar et Kir chemical constituents coumarins |
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