| 短暂性脑缺血发作生物学标志物研究进展 |
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| 引用本文： | 裴璐璐,方慧,赵璐,许予明,宋波.短暂性脑缺血发作生物学标志物研究进展[J].中国卒中杂志,2015,10(5):442-446. |
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| 作者姓名： | 裴璐璐 方慧 赵璐 许予明 宋波 |
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| 作者单位： | 450052 郑州郑州大学第一附属医院神经内科 |
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| 摘 要： | 短暂性脑缺血发作（transient ischemic attack，TIA）是卒中的危险预警信号。至今尚无公认的对卒中风险预测价值高的TIA的生物学标志物。寻找快速而准确的TIA后卒中风险的生物学标志物是目前研究的热点。本文从应激激素、炎症因子、血栓形成因子等方面对TIA后卒中风险的生物学标志物研究进行综述，并简要介绍基因测序及代谢组学等方法在TIA后卒中风险预测中的应用。
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| 关 键 词： | 短暂性脑缺血发作 卒中 预测 标志物 |
| 收稿时间： | 2014-10-25 |
Development of Biomarkers of Transient Ischemic Attack |
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| PEI Lu-Lu,FANG Hui,ZHAO Lu,XU Yu-Ming,SONG Bo..Development of Biomarkers of Transient Ischemic Attack[J].Chinese Journal of Stroke,2015,10(5):442-446. |
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| Authors: | PEI Lu-Lu FANG Hui ZHAO Lu XU Yu-Ming SONG Bo |
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| Institution: | Department of Neurology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China |
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| Abstract: | Transient ischemic attack (TIA) is an early-warning alarm for stroke. As of yet, no known blood marker reliably predicts stroke risk after TIA. The present research focuses on TIA biomarkers to identify high risk patients rapidly and accurately. In this article, we provide a review on the development of TIA biomarkers involving stress hormones, inflammatory factors, thrombosis factors. Meanwhile, the paper gives a brief introduction about gene sequencing and metabonomics methods in the application of stroke risk prediction after TIA. |
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| Keywords: | Transient ischemic attack Stroke Proediction Biomarkers |
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