| 双胎妊娠非整倍体异常的产前筛查与产前诊断 |
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| 引用本文： | 刘俊涛,周希亚. 双胎妊娠非整倍体异常的产前筛查与产前诊断[J]. 中国实用妇科与产科杂志, 2015, 31(7): 607-609. DOI: 10.7504/fk2015060108 |
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| 作者姓名： | 刘俊涛 周希亚 |
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| 作者单位： | 作者单位：中国医学科学院 北京协和医学院 北京协和医院妇产科，北京 100730 |
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| 摘 要： | 双胎妊娠非整倍体产前筛查较单胎复杂。应在早孕期确定孕周、绒毛膜性并测量颈项透明层厚度。早孕期联合筛查优于中孕期血清学筛查，但检出率明显低于单胎妊娠。无创产前检查用于双胎筛查仍需更多研究数据。双胎之一胚胎停育将影响早孕期筛查的准确性。产前诊断时区分标记双胎是需要注意的重要问题。
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| 关 键 词： | 双胎妊娠 产前筛查 产前诊断 无创产前检测 双胎之一胚胎停育 |
Prenatal screening and prenatal diagnosis of aneuploidy in twin pregnancy. |
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| LIU Jun-tao,ZHOU Xi-ya.. Prenatal screening and prenatal diagnosis of aneuploidy in twin pregnancy.[J]. Chinese Journal of Practical Gynecology and Obstetrics, 2015, 31(7): 607-609. DOI: 10.7504/fk2015060108 |
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| Authors: | LIU Jun-tao ZHOU Xi-ya. |
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| Affiliation: | Obstetrics and Gynecology Department，Peking Union Medical College Hospital，Peking Union Medical College，Chinese Academy of Medical Sciences，Beijing 100730，China |
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| Abstract: | Abstract:Prenatal aneuploidy screening is more complicated in twin pregnancy than in singleton pregnancy.Gestational age，chorionicity and NT should be determined at first trimester.Combined screening test at first trimester is better than second trimester screening，but the detection rate is lower than that of singleton pregnancy.NIPT in twins is still under research.Vanishing twins will surely affect the accuracy of prenatal screening.It is important to distinguish each twin when doing prenatal diagnosis. |
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| Keywords: | twin pregnancy prenatal screening prenatal diagnosis non-invasive prenatal test vanishing twins |
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