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胶原交联加强巩膜组织的研究进展
引用本文:张淼,张丰菊.胶原交联加强巩膜组织的研究进展[J].中华眼视光学与视觉科学杂志,2015,17(8):510-512.
作者姓名:张淼  张丰菊
作者单位:Zhang Miao,Zhang Fengju
基金项目:北京市教委科技计划重点项目(KZ201310025027);国家自然科学基金项目(81271041)
摘    要:胶原交联技术在眼科的应用已经得到不断发展,其能够显著加强胶原纤维的机械强度的作用已被充分肯定,巩膜胶原交联可阻止进展性近视的发展,已成为眼科医生的关注热点。现总结蓝光核黄素交联与传统的紫外线核黄素交联方法的优缺点,并提出了蓝光核黄素交联方法可能取代紫外线核黄素交联方法成为治疗进展性近视的趋势。

关 键 词:胶原  交联  核黄素  蓝光  巩膜  

Advanced research on collagen cross-linking for reinforcing the sclera
Zhang Miao,Zhang Fengju.Advanced research on collagen cross-linking for reinforcing the sclera[J].Chinese Journal of Optometry Ophthalmology and Visual Science,2015,17(8):510-512.
Authors:Zhang Miao  Zhang Fengju
Institution:Beijing Tongren Eye Center, Beijing Tongren Hospital,Capital Medical University, Beijing Ophthalmology and Visual Sciences Key Lab, Beijing 100730, China
Abstract:The use of collagen cross-linking is being developed continually due to its significance in the improvement of the mechanical strength of collagen fibers and its role in stopping myopia progression. This article discusses the advantages and disadvantages of traditional scleral UVA riboflavin cross-linking and blue-light riboflavin scleral cross-linking. The trend toward blue-light scleral cross-linking in replacing UVA cross-linking to prevent the progression of myopia is described in this review article.
Keywords:Collagen  Cross-linking  Riboflavin  Blue-light  Sclera  
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