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| PET/CT对头颈部肿瘤放射治疗计划的作用 | |
| 引用本文： | 向作林,曾昭冲,吴铮,管一晖,刘建军,陈刚.PET/CT对头颈部肿瘤放射治疗计划的作用[J].中华核医学杂志,2008,28(3). |
| 作者姓名： | 向作林 曾昭冲 吴铮 管一晖 刘建军 陈刚 |
| 作者单位： | 1. 复旦大学附属中山医院放疗科,上海,200052 2. 复旦大学附属华山医院PET中心 3. 上海交通大学医学院附属仁济医院PET/CT中心 |
| 摘 要： | 目的 探讨PET/CT对头颈部肿瘤放射治疗计划的作用.方法 16例头颈部肿瘤患者行PET/CT和定位CT检查,根据检查结果对16例患者进行TNM分期,比较其分期结果.将定位CT图像传入三维治疗计划系统(TPS),在定位CT图像上勾画大体肿瘤体积(GTV),即CT-GTV;参考PET/CT融合图像在定位CT图像上勾画PET/CT-GTV,比较PET/CT-GTV和CT-GTV.采用Stata 7.0软件分析数据,t检验用于比较PET/CT-GTV和CT-GTV.结果 PET/CT使7例患者TNM分期发生改变.PET/CT-GTV和CT-GTV中位值分别为84.3(46～364)cm3和116.2(58～472)cm3,差异有统计学意义(t=-4.3186, P=0.0005).结论 PET/CT能提高头颈部肿瘤分期和肿瘤靶区定位的准确性. |
| 关 键 词： | 头颈部肿瘤 放射治疗计划 计算机辅助 体层摄影术 发射型计算机 体层摄影术 X线计算机 脱氧葡萄糖 |
PET/CT fusion in radiotherapy treatment planning of head and neck cancer |
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| Abstract: | Objective The aim of this study was to investigate the value of PET/CT in radiation treatment planning of head and neck cancer. Methods Sixteen patients with head and neck cancer underwent PET/CT and enhanced CT imaging. TNM stage was analyzed based on PET/CT and CT. Gross tumor volume (GTV) of PET/CT (PET/CT-GTV) and CT (CT-GTV) were analyzed. Stata 7.0 was used for data analysis, PET/CT-GTV and CT-GTV were compared with t test. Results Based on PET/CT, changes in TNM stage occurred in 7 patients. The median PET/CT-GTV and CT-GTV were 84.3(46～364)cm3 and 116.2(58～472)cm3, respectively, which had a statistically significant difference (t=-4.3186, P=0.0005). Conclusion PET/CT can increase the accuracy of staging and defining the field and target volumes for radiation therapy of head and neck cancer. |
| Keywords: | Head and neck neoplasms Radiotherapy planning computer-assisted Tomography emission-computed Tomography X-ray computed Deoxyglucose |
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