In vitro activities of new quinolones against Brucella melitensis isolated in a tertiary-care hospital in Turkey |
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Authors: | S Kocagöz M Akova B Altun D Gür G Hasçelik |
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Institution: | Department of Medicine and Section of Infectious Diseases, Hacettepe University School of Medicine, Ankara, Turkey;Institute of Pediatrics, Hacettepe University School of Medicine, Ankara, Turkey;Clinical Pathology Laboratory, Hacettepe University School of Medicine, Ankara, Turkey;Tel: +90 312 311 1271 Fax: +90 312 310 4179 E-mail: |
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Abstract: | We have evaluated the in vitro activities of seven fluoroquinolones against 69 strains of Brucella melitensis . According to their minimum inhibitory concentration for 90% growth (MIC90) values, the most active agent was found to be sparfloxacin (MIC90 0.12 mg/L) followed by levofloxacin, ciprofloxacin, ofloxacin (MIC90 0.50 mg/L) and grepafloxacin (MIC90 1 mg/L), gemifloxacin (MIC90 2 mg/L) and gatifloxacin (MIC90 4 mg/L). |
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