Pharmacological adherence to oral anticoagulant and factors that influence the international normalized ratio stability |
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Authors: | Avila Christiane Wahast Aliti Graziella Badin Feijó Maria Karolina Ferreira Rabelo Eneida Rejane |
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Affiliation: | Hospital de Clínicas de Porto Alegre, Escola de Enfermagem, Universidade Federal do Rio Grande do Sul, RS, Brazil. chriswavila@yahoo.com.br |
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Abstract: | Cross-sectional study developed to relate the international normalized ratio (INR), used as a parameter to monitor the levels of blood clotting, stability to adherence, age, level of education, socioeconomic level, interaction with other drugs, comorbidities, vitamin K intake, anticoagulation time and drug cost. 156 patients were included, mean age 57 ± 13 years, (53.8%) male, 61 (39.1%) had high adherence, 91 (58.3%) medium and 4 (2.6%) low adherence to treatment, 117 (75%) had INR stability up to 50% and 39 (25%) > 75%, patients with shorter time of anticoagulation presented higher stability, those who spent less on the drug remained more stable and had better adherence. It was concluded that more than 90% of patients had high and medium adherence and that the anticoagulation time and drug cost were the factors related to the anticoagulation stability. |
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