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DCZ0415, a small‐molecule inhibitor targeting TRIP13, inhibits EMT and metastasis via inactivation of the FGFR4/STAT3 axis and the Wnt/β‐catenin pathway in colorectal cancer |
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| Authors: | Sumit Agarwal Farrukh Afaq Prachi Bajpai Hyung&#x;Gyoon Kim Amr Elkholy Michael Behring Darshan Shimoga Chandrashekar Sameer Al Diffalha Moh&#x;d Khushman Shajan P Sugandha Sooryanarayana Varambally Upender Manne |
| Institution: | 1. Department of Pathology, University of Alabama at Birmingham, AL, USA ; 2. O’Neal Comprehensive Cancer Center, University of Alabama at Birmingham, AL, USA ; 3. Department of Medicine, Division of Medical Oncology, University of Alabama at Birmingham, AL, USA ; 4. Department of Medicine, Division of Gastroenterology, University of Alabama at Birmingham, AL, USA |
| Abstract: | |
| Keywords: | colorectal cancer DCZ0415 FGFR4 granzyme B metastasis TRIP13 |