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The Genetics of Hypogammaglobulinemia
Authors:Bodo Grimbacher  Alejandro A. Schäffer  Hans-Hartmut Peter
Affiliation:(1) Division of Rheumatology and Clinical Immunology, Medical School, University of Freiburg, Hugstetterstrasse 55, 79106 Freiburg, Germany
Abstract:Etiologies for human hypogammaglobulinemias are diverse and include genetic and nongenetic causes. Although recent reviews focus on the complex genetics of common variable immunodeficiency, in this review, we survey different causes of hypogammaglobulinemias and discuss possible mechanisms.
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