The Genetics of Hypogammaglobulinemia |
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Authors: | Bodo Grimbacher Alejandro A. Schäffer Hans-Hartmut Peter |
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Affiliation: | (1) Division of Rheumatology and Clinical Immunology, Medical School, University of Freiburg, Hugstetterstrasse 55, 79106 Freiburg, Germany |
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Abstract: | Etiologies for human hypogammaglobulinemias are diverse and include genetic and nongenetic causes. Although recent reviews focus on the complex genetics of common variable immunodeficiency, in this review, we survey different causes of hypogammaglobulinemias and discuss possible mechanisms. |
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