NEONATAL PURPURA FULMINANS DUE TO HOMOZYGOUS PROTEIN C DEFICIENCY |
| |
Authors: | U. Ezer E. D. Misirlioglu V. Colba E. Ogoz C. Kurt |
| |
Affiliation: | Department of Pediatrics, Sun Yat-sen Memorial Hospital, Zhong Shan (Sun Yat-sen) University, Guangzhou, People's Republic of China |
| |
Abstract: | Severe and recurrent purpura fulminans developed in a Turkish boy at 1 week of age. Initial coagulation studies performed were compatible with disseminated intravascular coagulation. Subsequent investigations showed that the patient had homozygous and his healthy parents had heterozygous protein C deficiency. The episodes of purpura fulminans were controlled by infusions of fresh frozen plasma and heparinization. Oral anticoagulant therapy was given in the symptom-free period. |
| |
Keywords: | Homozygous Protein C Deficiency Newborn Purpura Fulminans |
|