End-Stage Renal Disease Following Carboplatin Chemotherapy for a Nasopharyngeal Carcinoma |
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| Authors: | Faissal Tarrass Mostafa Benmensour Abdelaziz Bayla |
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| Affiliation: | 1. Department of Nephrology and Dialysis, Ibn Rochd University Hospital Center, Casablanca, Moroccofaissal76@hotmail.com;3. Department of Oncology and Radiotherapy, Ibn Rochd University Hospital Center, Casablanca, Morocco |
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| Abstract: | Renal failure secondary to carboplatin therapy is due to acute tubular necrosis and is usually reversible. However, acute renal failure with rapid progression to end-stage renal disease is an exceedingly rare complication of carboplatin therapy. The authors report a case of definitive renal failure secondary to carboplatin chemotherapy for a nasopharyngeal carcinoma. The mechanisms that give rise to the chronic nephropathy are discussed. |
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| Keywords: | carboplatin cortical necrosis end-stage renal disease hemodialysis |
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