INTRACRANIAL INVOLVEMENT IN HODGKIN'S DISEASE |
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| Authors: | Canan Akyüz Bilgehan Yalcin İ. Lale Atahan Ali Varan M. Tezer Kutluk Münevver Büyükpamukçu |
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| Affiliation: | 1. Hacettepe University Institute of Oncology, Department of Pediatric Oncology, AnkaraTurkey;2. Hacettepe University Faculty of Medicine, Department of Radiation Oncology, AnkaraTurkey |
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| Abstract: | The authors report 3 cases of Hodgkin's disease with intracranial involvement. The patients were 4, 12, and 15 years old (male/female = 1/2). Initially, they were treated with ABVD or COPP chemotherapies and low-dose involved field radiotherapy. Intracranial recurrences occurred 27, 40, and 42 months after initial diagnosis, respectively. Two patients experienced convulsions and the other complained of diplopia. The metastatic lesions were located supratentorially with CT or MRI. Despite initial response achieved following systemic chemotherapy and external irradiation to cranial lesions, all patients died with disseminated disease. In patients with intracranial involvement of Hodgkin's disease, prolonged disease-free survival may be achieved by combined modality treatment. |
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| Keywords: | intracranial Hodgkin's disease prognosis treatment |
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