沙眼衣原体、解脲支原体感染致输卵管阻塞的临床分析

目的探讨沙眼衣原体、解脲支原体感染与输卵管阻塞的关系。方法回顾性分析我院不孕专科门诊300例不孕患者及健康对照组300例,宫颈分泌物行白带常规,支原体、衣原体检测及输卵管碘油造影术,进行对照研究。结果300例不孕患者中检出248例非淋球菌感染(CT感染85例,占28.33%;UU感染95例,占32.67%;CT UU混合感染68例,占22.67%)占82.66%(248/300)。对照组300例,检出非淋球菌感染15例(CT7例,占2.33%;UU6例,占2.0%;CT UU3例,占1.0%)占5%(15/300),两组相比,有显著性差异(P<0.001)。不孕组与对照组输卵管碘油造影结果比较,输卵管不完全阻塞率分别为42.67%(128/300)、5.67%(17/300),输卵管完全阻塞率分别为23.33%(70/300)、3.33%(10/300),两组相比,有显著性差异(P<0.001)。结论CT UU感染是引起输卵管阻塞的主要病因,建议行不孕检查及宫腔操作前,应将其列入常规检测,以便发现感染,及时治疗。

Tubal Obstruction Caused by Ureaplasma urealyticum and Chlamydia trachomatis Infection

Objective To investigate the relationship between Ureaplasma urealyticum (UU) and Chlamydia trachomatis (CT) infections and tubal obstruction. Methods 300 cases of infertilie women and 300 cases of healthy women were examined for leucorrhea,UU,CT and hysterosalpingography (HSG). Results 248 cases of non-gonococus infections were found in the infertility group, with a positive rate of 82.66% (248/300)(CT, UU and CT UU positive rates were 28.33% (85/300), 32.67% (95/300), and 22.67% (68/300),respectively). 15 cases of non-gonococus infections were fond in the control group, with a positive rate of 5% (15/300)(CT, UU and CT UU positive rates were 2.33% (7/300), 2.0% (6/300), 1.0% (3/300), respectively). There was a significant different between the two groups (P<0.001). HSG results showed that the rates of incomplete tubal obstruction of the infertile group and the control group were 42.67% (128/300) and 5.67% (17/300),respectively, while the rates of complete tubal obstruction were 23.33% (70/300) and 3.33% (10/300), respectively. The difference between these two groups was also significant, P<0.001. Conclusion The infection of UU and CT is the major pathogenic factor of tubal obstruction. It is necessary to detect UU and CT before infertile examination or uterine operation.