Relation between contractile reserve and improvement in left ventricular function with beta-blocker therapy in patients with heart failure secondary to ischemic or idiopathic dilated cardiomyopathy |
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| Authors: | Seghatol Frank F Shah Dipan J Diluzio Silvia Bello David Johnson Maryl R Cotts William G O'Donohue Jenny A Bonow Robert O Gheorghiade Mihai Rigolin Vera H |
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| Affiliation: | Division of Cardiology, Department of Medicine, Northwestern University, Feinberg School of Medicine, Chicago, Illinois, USA. |
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| Abstract: | Beta blockers improve left ventricular (LV) ejection fraction but patient responses are heterogenous. We investigated the role of contractile reserve (CR) in predicting beta-blocker response in ischemic and nonischemic cardiomyopathy. Resting and low-dose dobutamine echocardiograms were recorded in 32 patients with heart failure (LV ejection fraction
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