双水平正压通气治疗慢性阻塞性肺病并Ⅱ型呼吸衰竭的临床研究

目的 观察双水平正压通气治疗慢性阻塞性肺疾病合并Ⅱ型呼吸衰竭患者的疗效。方法 采用随机对照试验方法，治疗组30例均给予常规治疗并BiPAP呼吸机治疗，对照组26例仅给予常规治疗，观察两组治疗前后血气分析、临床症状、生命体征变化以及患者须加用的气管插管是否存在差异。结果 26例对照组中12例需气管插管或切开，30例治疗组中仅4例行气管插管或切开；治疗组患者血气分析、呼吸、心率改善优于对照组，差异有统计学意义（P〈0．05）。结论 双水平正压通气对COPD合并轻、中度Ⅱ型呼吸衰竭的患者疗效肯定，早期应用能减少气管插管率，有助于患者早日康复。

Effect of bi-level positive air pressure ventilation on chronic obstructive pulmonary diseases combined with respiratory failure

Objective To study the effect of bi-level positive air pressure ventilation on chronic obstructive pulmonary diseases(COPD)combined with respiratory failure. Methods A randomized controlled trial was used and routine therapy and BiPAP breathing apparatus were employed in 30 cases of the treatment group, while only routine therapy was used in the 26 cases of the control group. The differences of blood gas analysis, changes of vital signs, tracheal cannula rate of patients before and after treatment were compared between the two groups. Results The blood gas analysis, improvements of vital signs in the treatment group were better than those in the control group, and the differences were significant(P<0.05). Conclusion Bi-level positive air pressure ventilation has positive effects on patients of COPD combined with light and moderate respiratory failure.Its early application can reduce the tracheal cannula rate, which helps the recovery of patients.