轮状病毒性肠炎患儿血清心肌酶谱测定的临床意义

目的探讨轮状病毒性肠炎患儿血清心肌酶谱的改变及其临床意义。方法选择本院70例轮状病毒性肠炎患儿作为观察组,另选择同期70例非轮状病毒性肠炎患儿作为对照组。检测并比较2组治疗前、后的心肌酶谱天冬氨酸氨基转移酶(AST)、乳酸脱氢酶(LDH)、肌酸激酶(CK)、肌酸激酶同工酶(CK-MB)、α-羟丁酸脱氢酶(α-HBDH)]变化。结果观察组急性期心肌酶谱指标(AST、LDH、CK、CK-MB、α-HBDH)测定值高于对照组,且随着脱水程度的加重,其心肌酶谱呈升高趋势,差异均有统计学意义(P<0.05)。结论轮状病毒感染对心肌有不同程度的损害,早期进行心肌酶谱检测,并动态观察其变化,可及早发现心肌损害,指导临床治疗。

Clinical significance of myocardial enzyme spectrum determination of infants with rotavirus enteritis

Objective To investigate the change of serum myocardial enzyme spectrum and its clinical significance of infants with rotavirus enteritis.Methods 70 infants with rotavirus enteritis in children hospitalized were chosen as observation group,and 70 infants without rotavirus enteritis in children hospitalized were chosen as the control group.Checked and compared the change of the myocardial enzyme spectrum such as AST,LDH,CK,CKMB,α-HBDH of the 2 groups before and after treatment.Results The measured value of myocardial enzymes of the observation group were higher than that of the control group,and along with the aggravate of dehydration degree,the myocardial enzyme spectrum of which tended to rise,the differences were statistically significant（P〈0.05）.Conclusion Rotavirus infection had different degrees of the myocardial damage,checking myocardial enzyme spectrum early and observing the changes of that dynamically,can detect myocardial damage early and guide clinical treatment.