| 山茱萸大孔吸附树脂富集物中环烯醚萜苷含量的测定 |
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| 引用本文： | 李满郁,王巍,孟祥才,王喜军. 山茱萸大孔吸附树脂富集物中环烯醚萜苷含量的测定[J]. 中医药学报, 2010, 38(4): 43-45 |
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| 作者姓名： | 李满郁 王巍 孟祥才 王喜军 |
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| 作者单位： | 黑龙江中医药大学药学院,黑龙江,哈尔滨,150040 |
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| 基金项目： | 国家自然科学基金，黑龙江省科技攻关计划 |
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| 摘 要： | 目的：评价大孔吸附树脂富集山茱萸有效成分的应用效果。方法：UV法测定总苷的含量,RP-HPLC法测定莫诺苷及马钱苷的含量。结果：莫诺苷由药材含量的1.58%提高到51.00%,马钱苷由药材含量的0.62%提高到16.09%,总环烯醚萜苷由药材含量的4.54%提高到91.57%,结论：大孔吸附树脂富集工艺稳定,可显著提高成药的质量,从而生产出剂量小和质量稳定的可控制剂。
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| 关 键 词： | 莫诺苷 马钱苷 环烯醚萜总苷 |
Determination of the Iridoid Glycoside in Fructas Macrocarpii Enriched by Macroporoas Resin |
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| LI Man-yu,WANG Wei,MENG Xiang-cai,WANG Xi-jun. Determination of the Iridoid Glycoside in Fructas Macrocarpii Enriched by Macroporoas Resin[J]. Acta Chinese Medicine and Pharmacology, 2010, 38(4): 43-45 |
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| Authors: | LI Man-yu WANG Wei MENG Xiang-cai WANG Xi-jun |
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| Affiliation: | (Heilongjiang University of Chinese Medicine,Harbin 150040,China) |
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| Abstract: | Objective： To evaluate the utilization effectiveness of the active ingredient of Fructus Macrocarpii enriched by macroporous resin.Methods： The content of the total glycosides was determined by meas of UV;the content of morroniside and loganin were determined using RP-HPLC.Results： Compared with material content,the morroniside content was increased from 1.58% to 51.00%,the loganin content was enhanced from 0.62% to 16.09%,the total iridoid glycoside content was improved from 4.54% to 91.57%,respectively.Conclusion： Macroporous resin enrichment process was stable and could significantly improve the quality of medicines,and thus could produce the small dose and stable quality control preparation |
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| Keywords: | Morroniside Loganin Total iridoid glycoside |
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