Observations of aggressive,small, flat,and depressed colon cancer |
| |
Authors: | A. Kasumi G. L. Kratzer M. Takeda |
| |
Affiliation: | (1) Department of Gastroenterology, Jefferson Medical College, 19107 Philadelphia, PA, USA;(2) Colon and Rectal Surgery Department, Sacred Heart Hospital, 421 Chew Street, 18102 Allentown, PA, USA;(3) Department of Laboratory Sciences, College of Allied Health Sciences, Thomas Jefferson University, 19107 Philadelphia, PA, USA;(4) Noguchi Medical Research Institute, 3600 Market Street, Suite 350, 19104 Philadelphia, PA, USA |
| |
Abstract: | Three cases of small, flat, and depressed colon cancers are reported. One lesion is less than 1 cm in diameter with lymphatic invasion in the submucosa; the other measures 0.8 cm in the longest dimension and penetrates through the muscular layers to the subserosa. The third one, 1.2 cm in diameter, has had liver metastasis. The endoscopic appearances of two lesions with a resected specimen are presented in color to demonstrate some difficulties in visualizing these lesions for endoscopists. The biologic aggressiveness of these three lesions appears due to their rapid growth, which is expressed by a high mitotic rate of the cancer cells. Their histogenesis is considered to derive from (1) flat adenoma, from (2) serrated adenoma, and (3) from hyperplastic epithelium (or de novo in origin), respectively. |
| |
Keywords: | Small flat cancer of the colon Small depressed cancer of the colon Flat adenoma Serrated adenoma De novo cancer of the colon |
本文献已被 SpringerLink 等数据库收录! |
|