可吸收膜预防鸡肌腱粘连的实验研究

目的探讨鸡肌腱断裂修补后,可吸收膜预防肌腱粘连的可行性及其有效性,为预防肌腱粘连提供一种新的方法。方法将30只12周的Leghorn鸡随机分为2组,A组为空白组,B组为可吸收膜组,每组15只。对每只鸡的左、右足第三趾(最长趾)进行断裂修补。A组修补后不放置可吸收膜,B组修补后放置可吸收膜。修补术后2、4、6周分别进行组织形态学、生物力学及功能恢复的测定,同时进行两组间比较的统计学分析。结果肉眼下可吸收膜组同周围组织粘连较少,光镜下可吸收膜组未见明显坏死组织,同周围组织之间的瘢痕较少。6周后两组肌腱的生物力学结果无明显差异,但可吸收膜组近节趾间关节及掌趾关节的屈曲功能明显优于空白组。结论可吸收膜可作为一种预防肌腱粘连的新方法。

An experimental study of absorbable membrane in prevention of tendon adhesion in chicken

Objective To investigate the effect of absorbable membrane on prevention of tendon adhesion after the ruptured tendon is repaired. Methods In our experiment, 30 12-weeks-old Leghorn cocks were divided into 2 groups randomly. Group A was the blank group, and Group B was the absorbable membrane group. Each group had 15 cocks. The flexor tendon of third phalanx was made ruptured. After repairing, histological observation, failure mode test and functional recovery test were performed regularly. Results In Group B, there was little adhesion between tendon and normal tissue under gross observation. There was no significant tissue necrosis or scar tissue under microscope. There was no difference in the failure mode test between the 2 groups 6 weeks after repairing. The functions of movement of interphalangeal and metacarpophalangeal joints in group B were better than those in group A. Conclusion The absorbable membrane can be a kind of material or method used to prevent tendon adhesion.