| 多指标综合评分法优化更年康颗粒醇提工艺 |
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| 引用本文： | 熊汝菊,毛春芹,谈瑄忠.多指标综合评分法优化更年康颗粒醇提工艺[J].中国中医药信息杂志,2008,15(4):61-63. |
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| 作者姓名： | 熊汝菊 毛春芹 谈瑄忠 |
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| 作者单位： | 1. 南京中医药大学药学院,江苏,南京,210046
2. 南京市中医院药剂科,江苏,南京,210001 |
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| 摘 要： | 目的优化更年康颗粒的醇提工艺。方法采用正交试验设计，以芍药苷、黄芪甲苷含量为评定指标，用多指标综合评分法进行数据处理，优化提取条件。结果更年康颗粒优化醇提工艺为18倍量70％乙醇，分3次回流提取，每次1．5h。结论该提取工艺合理，有效成分提取效率高。
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| 关 键 词： | 更年康颗粒 芍药苷 黄芪甲苷 正交实验 综合评分法 |
| 文章编号： | 1005-5304(2008)04-0061-03 |
| 修稿时间： | 2007年7月26日 |
Optimization of the Extraction Technology for Gengniankang Granules with the Multiple Guidelines Grading Method |
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| XIONG Ru-ju,MAO Chun-qin,TAN Xuan-zhong.Optimization of the Extraction Technology for Gengniankang Granules with the Multiple Guidelines Grading Method[J].Chinese Journal of Information on Traditional Chinese Medicine,2008,15(4):61-63. |
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| Authors: | XIONG Ru-ju MAO Chun-qin TAN Xuan-zhong |
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| Institution: | XIONG Ru-ju,MAO Chun-qin,TAN Xuan-zhong(1.Pharrnaceutical College of Nanjing University of TCM, Nanjing 210046, China; 2. Nanjing Hospital of TCM, Nanjing 210001, China) |
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| Abstract: | Objective To optimize the extraction technology for GengnianKang Granules.Methods An orthogonal test was adopted in the study. The contents of Paeoniflorin and Astragaloside Ⅳ were used as indices of appraisal. Data processing was carried out with the multiple guidelines grading method for optimizing the extraction condition. Results The optimized extraction technology for Gengniankang Granules was shown to be： eighteen fold volume of 70% alcohol should be added to 1 volume of the granules for 3 successive reflux extractions with 1.5 h of each. Conclusion The optimized extraction technology was rational and the extraction rate of the active components was high. |
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| Keywords: | Gengniankang Granules Paeoniflorin Astragaloside IV orthogonal test grading methods |
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