2010—2013年南京市成年居民代谢综合征患病情况及流行特征

目的了解南京市成年居民代谢综合征(MS)的患病情况以及流行特征。方法 2010—2013年,采用多阶段分层与人口成比例的整群随机抽样的方法,共调查南京市成年居民4918人。对调查对象进行问卷调查、体格检查和实验室检查,收集调查对象的基本情况、个人健康情况以及身高、体重、腰围、血压、空腹血糖、总胆固醇、甘油三酯、高密度脂蛋白胆固醇等相关指标。MS患者的筛查采用2009年国际联合暂定声明(JIS)诊断标准。结果 4918名调查对象中有1627人患MS,粗患病率为33.1%,年龄标化患病率为26.3%,男性MS年龄标化患病率为29.0%,女性为24.8%,不同性别之间的年龄标化患病率差异无统计学意义(χ~2=1.352,P=0.245)。不同年龄段(χ~2=132.557,P<0.001)、职业(χ~2=87.572,P<0.001)、文化程度(χ~2=26.077,P<0.001)的调查对象MS患病率间差异均有统计学意义。有高血压(χ~2=26.582,P<0.001)、糖尿病(χ~2=16.013,P<0.001)家族史的调查对象MS患病率更高。结论 2010—2013年南京市成年居民代谢综合征患病率较高。

Prevalence and epidemic characteristics of metabolic syndrome among adult residents in Nanjing City in 2010-2013

OBJECTIVE To understand the prevalence and epidemic characteristics of metabolic syndrome (MS)among adult residents in Nanjing City. METHODS In 2010-2013,a total of 4918 adult residents in Nanjing City were surveyed using a multi-stage stratification and population proportional clustering random sampling method.Questionnaires,physical examinations and laboratory examinations were conducted to collect the basic conditions,health history of the subjects and related indicators including height,weight,waist circumference,blood pressure,fasting blood glucose,total cholesterol,triglycerides,high-density lipoprotein cholesterol,etc.The 2009 International Joint Interim Statement (JIS)was used to filter patients with metabolic syndrome.RESULTS Among the 4918 surveyed subjects,1627 were MS,with a crude prevalence rate of 33.1% and an age-standardized prevalence rate of 26.3%,the standardized prevalence rate of MS was 29.0% in males and 24.8%in females.Agestandardized prevalence rates between different genders had no significant statistical difference (X^2 =1.352,P =0.245).There were significant statistical differences between the crude prevalence rate of MS among subjects of different ages (X^2=132.557,P < 0.001),occupations (X^2 =87.572,P <0.001 )and educational level (X^2 =26.077,P < 0.001).Patients with a family history of hypertension (X^2 =26.582,P <0.001 )and a family history of diabetes (X^2 =16.013,P <0.001 )had a higher prevalence of MS. CONCLUSION The prevalence of metabolic syndrome in adult residents in Nanjing City in 2010-2013 was relatively high.