| 187例喹诺酮类药物致不良反应分析 |
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| 引用本文： | 程军,王刚斌,张士勇,王儒强.187例喹诺酮类药物致不良反应分析[J].药物流行病学杂志,2010(3):131-133. |
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| 作者姓名： | 程军 王刚斌 张士勇 王儒强 |
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| 作者单位： | 东南大学附属蚌埠市第三人民医院药剂科; |
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| 摘 要： | 目的：了解我院喹诺酮类药致不良反应发生特点与一般规律。方法：对2007～2008年我院ADR监测中心收集到的187例喹诺酮类药致ADR报表进行汇总分析。结果：187例ADR报表中涉及6种喹诺酮类药，最常见的不良反应是皮肤及其附件损害和消化系统反应，多数不良反应的转归情况良好，注射剂容易引起ADR，发生ADR的喹诺酮类药以加替沙星最多。结论：喹诺酮类药发生ADR与多种因素相关，临床使用时应高度重视喹诺酮类药不良反应的监测，减少ADR的发生。
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| 关 键 词： | 药品不良反应 喹诺酮类药 合理用药 |
Analysis of 187 Cases of ADRs Induced by Quinolones |
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| Cheng Jun,Wang Gangbin,Zhang Shiyong,Wang Ruqiang Dept.of Pharmacy,Third Bengbu People\''s Hospital,Bengbu,Anhui,China.Analysis of 187 Cases of ADRs Induced by Quinolones[J].Chinese Journal of Pharmacoepidemiology,2010(3):131-133. |
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| Authors: | Cheng Jun Wang Gangbin Zhang Shiyong Wang Ruqiang Deptof Pharmacy Third Bengbu People\'s Hospital Bengbu Anhui China |
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| Institution: | Cheng Jun,Wang Gangbin,Zhang Shiyong,Wang Ruqiang Dept.of Pharmacy,Third Bengbu People\'s Hospital,Bengbu 233000,Anhui,China |
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| Abstract: | Objective： To investigate the characteristics and regularities of adverse drug reactions （ADRs） induced by quionlones antibacterial agents in our hospital. Methods： 187 ADR cases induced by quionlones collected by the ADR drugs monitoring center in our hospital from 2007 -2008 were classified and analyzed. Results：187 ADR cases were involved in 6 drugs of quionlones. The ADRs were chiefly manifested as lesions of skin and its accessories, and followed by the reaction of the digestive system. Most ADRs induced by the intravenous route had a good recovery. Quionlones causing most ADRs was gatifloxacin. Conclusion： The occurrence of ADRs caused by quionlones was related to many factors. Great importance should be attached to ADR monitoring so as to reduce the incidence of ADRs by quionlones . |
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| Keywords: | Adverse drug reaction Quionlones Rational drag use |
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