猪腹主动脉下端不同程度狭窄致股总动脉血流动力学改变的研究

目的 探讨腹主动脉下端不同程度狭窄引起股总动脉血流动力学的改变.方法 幼年家猪6只,利用血管夹夹闭腹主动脉下端侧壁依次造成1/3、1/2、2/3、3/4管腔狭窄,记录对应股总动脉血流流速曲线波形.测算收缩期峰值速度(PSV)、舒张期最小速度(MDV)、PSV/MDV(S/D)、MDV/PSV(D/S).分析所有实验数据并进行统计学处理,观察血流参数与狭窄程度的相关性.结果 狭窄达到一定程度后反向波消失并转为止向波.PSV与狭窄程度呈线性负相关(R=0.983,R2=0.967),D/S在管腔狭窄超过1/3后与狭窄程度呈线性正相关(R=0.918,R2=0.843).结论 可以根据血流流速曲线波形的改变推断其上游存在狭窄性病变和反映狭窄下游有效循环血流量的情况,PSV、D/S结合流速曲线波形是有效的评价方法.

The common femoral artery haemodynamics caused by different degrees of abdominal aorta extremity stenosis in swines

Objective To study the common femoral artery haemodynamics caused by different degrees of abdominal aorta extremity stenosis.Methods The lateral walls of abdominal aorta extremity were pinched with vascular clamp resulting in 1/3,1/2,2/3,3/4 stenosis by turns in 6 juvenile susscrota domesticas.The parameters of peak systolic velocity(PSV),minimum diastolic velocity(MDV),PSV/MDV(S/D)and MDV/PSV(D/S)of common femoral artery were obtained and their correlations with degrees of abdominal aorta extremity stenosis were confirmed by statistical analysis.Results The backwardware vanished or turned to forwardware when stenosis achieved certain degree.PSV had significant negative correlation with stenosis degree(R=0.985,R2=0.969),but D/S had significant positive correlation with stenosis degree when stenosis degree exceed 1/3(R=0.918,R2=0.843).Conclusions It can be concluded there is proximal stenosis disease and change of distal effective circulating blood volume according to the Doppler velocity tracing analysis.PSV and D/S are valuable parameters,however waveform should be ignored.