Inflammatory pseudotumor of the spleen. Review and a new case report

Splenic inflammatory pseudotumour has been defined as a benign tumour reactive lesion with unspecified reparative or inflammatory alterations. It is a mimicking tumour often confused with other pathologies, primarily, lymphoproliferative disorders. Though its aetiology remains unknown, these tumours are often associated to infectious agents such as the Epstein-Barr virus. We describe a case of a 29 year-old patient with a history of infectious mononucleosis, followed by fever, weight loss, and splenomegaly. Splenectomy detected a homogeneous, whitish 2 cm node diagnosed as splenic inflammatory pseudotumour. The clinical features and diagnosis of this disorder are discussed in relation to the histopathological findings.