| Stimulation of locus coeruleus increases arterial pressure in rabbits |
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| 引用本文： | 陈永跃,黄仲荪. Stimulation of locus coeruleus increases arterial pressure in rabbits[J]. Acta pharmacologica Sinica, 1997, 0(5) |
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| 作者姓名： | 陈永跃 黄仲荪 |
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| 作者单位： | 重庆医科大学生理教研室 |
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| 摘 要： | 目的：研究电刺激和化学刺激兔蓝斑（ＬＣ）对动脉血压（ＡＰ）和肾交感神经传出活动（ＲＳＡ）的影响．方法：电刺激ＬＣ，ＬＣ微量注射ＬＧｌｕ、盐酸吗啡、ＧＡＢＡ、电解毁损ＬＣ，记录ＡＰ和ＲＳＡ．结果：电刺激ＬＣ和ＬＣ注射ＬＧｌｕ均引起ＡＰ升高（分别为１３５±０３ｖｓ１９５±０８ｋＰａ和１３８±０４ｖｓ１７５±０８ｋＰａ）和ＲＳＡ增加．ＬＣ注射吗啡、ＧＡＢＡ对ＡＰ和ＲＳＡ无明显影响．电解毁损ＬＣ后电刺激ＬＣ区、ＬＣ区注射ＬＧｌｕ对ＡＰ和ＲＳＡ无明显影响．结论：兔ＬＣ兴奋引起ＡＰ升高和ＲＳＡ增加，但ＬＣ不是ＡＰ和ＲＳＡ的紧张性中枢．
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| 关 键 词： | 蓝斑；谷氨酸；γ-氨基丁酸；吗啡；交感神经系统；血压 |
Stimulation of locus coeruleus increases arterial pressure in rabbits |
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| CHEN Yong Yue ,HUANG Zhong Sun. Stimulation of locus coeruleus increases arterial pressure in rabbits[J]. Acta pharmacologica Sinica, 1997, 0(5) |
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| Authors: | CHEN Yong Yue HUANG Zhong Sun |
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| Affiliation: | CHEN Yong Yue 1,HUANG Zhong Sun |
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| Abstract: | |
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| Keywords: | locus coeruleus glutamates GABA morphine sympathetic nervous system blood pressure |
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