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探讨血小板计数在血泵离体实验中的意义
引用本文:徐世伟,陈芳,陈如坤,丁铭君. 探讨血小板计数在血泵离体实验中的意义[J]. 生物医学工程学杂志, 2002, 19(2): 297-299
作者姓名:徐世伟  陈芳  陈如坤  丁铭君
作者单位:浙江大学,医学院附属第二医院,心胸外科,杭州,310009
基金项目:浙江省卫生厅资助项目 (M-963 4)
摘    要:为了探讨血小板计数在血泵离体实验中的意义。我们用两种滚压泵分成两组,作5对16小时离体长时间转流实验,血样本为转前作对照组、转流4h后每隔2h抽1次。测定项目:血小板计数、游离血红蛋白。结果:两组血小板计数值均随转流时间延长而呈线性逐渐增加,各时点值与前时点比(P<0.05),有显著差异,两组游离血红蛋白量也随转流时间延长而呈线性增加。血小板计数与游离血红蛋白呈直线回归相关关系。结论;在血泵离体转流实验中,血小板计数可反映血细胞碎片的数量,因此可作为一项评价血泵离体溶血性能的客观指标。

关 键 词:血小板计数 血泵 离体实验 人工血泵 溶血

Assessing the Significance of Platelet Count to In-Vitro Hemolytic Test by Roller Pump
Xu Siwei Chen Fang Chen Rukun Ding Mingjun. Assessing the Significance of Platelet Count to In-Vitro Hemolytic Test by Roller Pump[J]. Journal of biomedical engineering, 2002, 19(2): 297-299
Authors:Xu Siwei Chen Fang Chen Rukun Ding Mingjun
Affiliation:Department of Cardiovascular Surgery, 2nd Affiliated Hospital, Zhejing University School of Medicine, Hangzhou 310009.
Abstract:This study was directed at estimating the value of platelet count in the course of in vitro hemolytic tests by roller pump. Five paired in vitro tests were conducted using the POLYSTAN pump(group A) and COBE pump(group B). The pumps ran 16 hours. The samples for platelet count and plasma free hemoglobin were taken before pumping, and every 2 hours after 4 hours of pumping. The 2 groups' platelet count and plasma free hemoglobin levels were found to be linearly increasing with the hours of pumping and linear regression analysis showed the platelet count and plasma free hemoglobin were positively correlated. These data suggested that platelet count could be used as an index in evaluating the in vitro hemolytic properties of blood pumps.
Keywords:Platelet count Roller pump Hemolysis
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