| Pulmonary alveolar proteinosis treated with whole-lung lavage utilizing extracorporeal membrane oxygenation:a case report and review of literatures |
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| 作者姓名： | 蔡后荣 崔叔阳 金陵 黄贻真 王喆研 曹彬 母国华 王尔东 周贤梅 |
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| 作者单位： | Department of Pulmonary Medicine，Affiliated Drum Tower Hospital，Nanjing University School of Medicine，Nanjing 210008，China，Department of Pulmonary Medicine，Affiliated Drum Tower Hospital，Nanjing University School of Medicine，Nanjing 210008，China，Department of Pulmonary Medicine，Affiliated Drum Tower Hospital，Nanjing University School of Medicine，Nanjing 210008，China，Department of Pulmonary Medicine，Affiliated Drum Tower Hospital，Nanjing University School of Medicine，Nanjing 210008，China，Department of Pulmonary Medicine，Affiliated Drum Tower Hospital，Nanjing University School of Medicine，Nanjing 210008，China，Department of Pulmonary Medicine，Affiliated Drum Tower Hospital，Nanjing University School of Medicine，Nanjing 210008，China，Department of Pulmonary Medicine，Affiliated Drum Tower Hospital，Nanjing University School of Medicine，Nanjing 210008，China，Department of Pulmonary Medicine，Affiliated Drum Tower Hospital，Nanjing University School of Medicine，Nanjing 210008，China，Department of Pulmonary Medicine，Affiliated Drum Tower Hospital，Nanjing University School of Medicine，Nanjing 210008，China |
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| 摘 要： | Pulmonaryalveolarproteinosis (PAP )wasfirstdescribedbyRosenetal1 in 195 8 PAPischaracterizedbytheaccumulationof proteinaceousmaterialinthealveolileadingtovaryingdegreesofimpairmentin gasexchange Recentstudiesdemonstratethatdeficiencyofgranulocyte macrophagecolonystimulatingfactor (GM CSF )isastronglysuspectedmechanismforadultacquiredPAP ,andsubcutaneousadministrationofrecombinanthumanGM CSFiseffectiveinapproximately 5 0 %ofpatientswithPAP ;2 4 butwholelunglavage (WLL)remainsthemo…
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