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Left thalamomegaly in a patient with partial epilepsy
Authors:Della Marca Giacomo  Vollono Catello  Ferraro Diana  Mariotti Paolo  Mazza Marianna  Ferini-Strambi Luigi  Mazza Salvatore
Institution:Department of Neurosciences, Catholic University, Rome, Italy. dellamarca@rm.unicatt.it
Abstract:Temporal lobe epilepsy (TLE) is associated with modification in thalamic structure and function. In particular, thalamic atrophy and hypometabolism can occur, affecting ipsilateral, contralateral thalami or both. We describe a 28-year-old epileptic woman, who presented peculiar neuroimaging findings, with enlargement of the thalamus contralateral to the epileptic focus. The patient was born from dystocic delivery, she presented partial motor seizures in the left side of the body, followed by generalisation, and the EEG showed a right temporal epileptic focus. Serial CT and MRI scan, performed along 11 years, showed a non-evolutive left thalamomegaly. 18-FDG PET showed reduced metabolic activity in the upper right temporal gyrus and in the ipsilateral thalamus. Thalamic asymmetry in our patient could be an occasional finding.
Keywords:Epilepsy  Thalamus  Magnetic resonance imaging  Positron emission tomography  Asymmetry  Perinatal hypoxia
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