| 臭灵丹化学成分的研究 |
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| 引用本文： | 刘百联,张婷,张晓琦,叶文才,李药兰.臭灵丹化学成分的研究[J].中国中药杂志,2010,35(5):602-606. |
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| 作者姓名： | 刘百联 张婷 张晓琦 叶文才 李药兰 |
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| 作者单位： | 1. 暨南大学,中药及天然药物研究所,广东,广州,510632;暨南大学,中药药效物质基础及创新药物研究广东省重点实验室,广东,广州,510632
2. 暨南大学,中药及天然药物研究所,广东,广州,510632;无锡药明康德新药开发有限公司,上海,200131 |
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| 基金项目： | 教育部重点项目(106155);广东省自然科学基金团队项目(8351063201000003) |
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| 摘 要： | 目的:研究臭灵丹的化学成分。方法:采用硅胶、ODS和Sephadex LH-20等色谱手段分离臭灵丹乙醇提取物的化学成分;根据化学反应和波谱数据鉴定所得化合物结构。结果:从中分离得到19个化合物,分别鉴定为臭灵丹二醇(1),冬青酸(2),洋艾素(3),金腰素乙(4),3,5-二羟基-6,7,3′,4′-四甲氧基黄酮(5),猫眼草酚(6),5,6,4′-三羟基-3,7-二甲氧基黄酮(7),槲皮素(8),柽柳素(9),万寿菊素(10),槲皮素-3-O-β-D-半乳吡喃糖苷(11),万寿菊素-3-O-β-D-吡喃葡萄糖苷(12),槲皮素-3-O-(6-p-香豆酰基)-β-D-吡喃葡萄糖苷(13),4′,5,7-三羟基-6-甲氧基黄酮-3-O-β-D-芸香糖苷(14),山柰酚-3-O-β-D-吡喃葡萄糖苷(15)、豆甾醇(16)、豆甾醇-3-O-β-D-吡喃葡萄糖苷(17)、邻羟基苯甲酸(18)、β-谷甾醇(19)。结论:化合物5,7,9~15,17~18为首次从该植物中分离得到,化合物7的13C-NMR数据由本文首次报道。
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| 关 键 词： | 臭灵丹 化学成分 倍半萜 黄酮 甾醇 |
| 收稿时间： | 7/6/2009 12:00:00 AM |
Chemical constituents of Laggera pterodonta |
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| LIU Bailian,ZHANG Ting,ZHANG Xiaoqi,YE Wencai and LI Yaolan.Chemical constituents of Laggera pterodonta[J].China Journal of Chinese Materia Medica,2010,35(5):602-606. |
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| Authors: | LIU Bailian ZHANG Ting ZHANG Xiaoqi YE Wencai and LI Yaolan |
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| Institution: | Institute of Traditional Chinese Medicine & Natural Products, Ji'nan University,Guangzhou 510632, China;Guangdong Province Key Laboratory of Pharmacodynamic Constituents of Traditional Chinese Medicine and New Drugs Research, Ji'nan University, Guangzhou 510632, China;Institute of Traditional Chinese Medicine & Natural Products, Ji'nan University,Guangzhou 510632, China;Wuxi PharmaTech Co., Ltd., Shanghai 200131, China;Institute of Traditional Chinese Medicine & Natural Products, Ji'nan University,Guangzhou 510632, China;Guangdong Province Key Laboratory of Pharmacodynamic Constituents of Traditional Chinese Medicine and New Drugs Research, Ji'nan University, Guangzhou 510632, China;Institute of Traditional Chinese Medicine & Natural Products, Ji'nan University,Guangzhou 510632, China;Guangdong Province Key Laboratory of Pharmacodynamic Constituents of Traditional Chinese Medicine and New Drugs Research, Ji'nan University, Guangzhou 510632, China;Institute of Traditional Chinese Medicine & Natural Products, Ji'nan University,Guangzhou 510632, China;Guangdong Province Key Laboratory of Pharmacodynamic Constituents of Traditional Chinese Medicine and New Drugs Research, Ji'nan University, Guangzhou 510632, China |
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| Abstract: | |
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| Keywords: | Laggera pterodonta chemical constituents sesquiterpenoids flavonoids sterols |
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