原发性羊水过少与妊娠并发症的关系及对妊娠结局的影响

目的探讨原发性羊水过少与妊娠并发症的关系及对妊娠结局的影响。方法收集我院2008年2月～2010年2月住院治疗的原发性羊水过少孕妇106例,随机抽取同期我院分娩的羊水量正常孕妇120例作为对照组,两组孕妇就妊娠并发症、围生儿及母体情况进行比较。结果原发性羊水过少组中延期过期妊娠、妊娠期肝内胆汁瘀积症（ICP）、胎儿宫内发育受限（FGR）、妊娠高血压疾病（PIH）及胎儿畸形发生率均高于对照组,差异有统计学意义（P〈0.01,P〈0.05）,羊水过少组中同时合并两种、三种妊娠并发症的发生率均较对照组高,差异具有统计学意义（P〈0.01）,胎儿宫内窘迫、新生儿窒息及羊水粪染的发生率也明显升高（P〈0.05,P〈0.01）。伴有妊娠并发症的羊水过少孕妇,其胎儿宫内窘迫及羊水Ⅱ、Ⅲ度粪染率远较无妊娠并发症孕妇高（P〈0.01）。剖宫产及产后出血发生率较对照组高（P〈0.05）。结论原发性羊水过少与妊娠并发症密切相关,可作为许多妊娠并发症的危险信号。原发性羊水过少严重威胁围生儿生命,造成不良妊娠结局;如果同时合并妊娠并发症则风险更大。做好产前严密的检测,积极治疗妊娠并发症,适时地选择合适的分娩方式是提高出生质量的重要方法。

The association of primary oligohydramnios with pregnancy complications and effect on pregnancy ending

Objective To explore the association of primary oligohydramnios with pregnancy complications and effect on pregnancy ending.Methods The clinical data of 106 patients with primary oligohydramnios in our hospital from February 2008 to February 2010 were collected.120 patients with normal amniotic fluid volume were selected randomly as control group.The complications of pregnancy and adverse perinatal outcomes were analyzed.Results Compared to control group,incidences of postterm or overdue pregnancy,intrahepatin cholestasis of pregnancy（ICP）,fetal growth restriction（FGR）,pregnancy-induced hypertension syndrome（PIH）and fetal anomalies,in primary oligohydramnios group was obviously high and had significant difference（P0.01,P0.05）.The incidences of two or three kinds of pregnancy complications in primary oligohydramnios group were significant higher than that of control group（P0.01）.Occurrence of fetal distress,newborn asphyxia,and meconium-stained fluid increased in this group（P0.01,P0.05） too.The rate of fetal distress,Ⅱ or Ⅲ meconium-stained fluid in patients with oligohydramnios complicated with pregnancy complications was higher than that of primary oligohydramnios patients without pregnancy complications（P0.01）. The incidences of uterine-incision delivery and postpartum hemorrhage are also higher than that of control group（P0.05）.Conclusion Intimate association of primary oligohydramnios with pregnancy complications is identified,primary oligohydramnios can be seen as a risk signal of many pregnancy complications.Primary oligohydramnios severely threaten perinatal life and causes harmful of parturition and the risk will increase if primary oligohydramnios patients complicated with pregnancy complications.Accomplishment of strict prenatal examination,To active treat pregnancy complications and choice of appropriate method for delivery at the right moment are important in improving the birth quality.