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影响慢性肾病患者肾功能危险因素的逐步回归分析
引用本文:关欣,李力,杜欣.影响慢性肾病患者肾功能危险因素的逐步回归分析[J].贵阳医学院学报,2010,35(4):374-376.
作者姓名:关欣  李力  杜欣
作者单位:沈阳军区总医院肾脏病科,辽宁,沈阳,110016
摘    要:目的:通过分析慢性肾病患者的临床参数及病理指标,探讨影响慢性肾病患者肾功能的危险因素。方法:选345例经肾活检确诊的慢性肾病患者的临床及病理资料,采用逐步回归方法探讨影响肾功能的危险因素。结果:逐步回归分析结果表明选入逐步回归方程的因素有血压、24 h尿蛋白定量、血尿酸、肾小球硬化和肾间质纤维化。结论:高血压、24 h尿蛋白定量、血尿酸、肾小球硬化和肾间质纤维化是影响慢性肾病患者肾功能的高危因素。

关 键 词:肾病  肾功能试验  危险因素  回归分析

Stepwise Regression Analysis of the Risk Factors Affecting Kidney Function in Patients with Chronic Kidney Disease
GUAN Xin,LI Li,DU Xin.Stepwise Regression Analysis of the Risk Factors Affecting Kidney Function in Patients with Chronic Kidney Disease[J].Journal of Guiyang Medical College,2010,35(4):374-376.
Authors:GUAN Xin  LI Li  DU Xin
Institution:( Department of Nephrology, General Hospital of Shenyang Military Area Command of Chinese PLA, Shenyang 110016, Liaoning, China )
Abstract:Objective: To study the risk factors affecting kidney function in patients with chronic kid- ney disease by analysis of clinical parameters and pathologyical indexes. Methods: Clinical and pathological data of 345 patients with chronic kidney disease confirmed by renal biopsy were analyzed by using multivariate stepwise regression models to explore risk factors of kidney function. Results: Factors that showed effects on kidney function were 24 h urine protein, hypertension, blood uric acid, ulosclerosis and interstitialfibrosis. Conclusions: Hypertension, 24 h urine protein, glomerulosclerosis, renal interstitialfibrosis and blood uric acid are high risk factors affecting kidney function in patients with chronic kidney disease.
Keywords:nephrosis  kidney ruction tests  risk factors  regression analysis
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