微电极导向同期行丘脑及苍白球腹后部毁损治疗帕金森病

目的：观察微电极导向对丘脑腹外侧核（vim/vop核）苍白球腹后部（pvp核）联合毁损术对帕金森病的临床疗效。方法：应用微电极导向技术对30例帕金森病（PD）患者，同侧丘脑腹外侧核（vim/vop)及苍白球腹后部（pvp)进行联合毁损术。结果：30例PD患者，其中不同症状改善率分别为：震颤100%，僵硬91.3%,运动迟缓87.3%,“关”状态76.3%，无永久的并发症。结论：应用微电极导向立体定向技术对伴有震颤、僵硬。运动迟缓及“开”“关”状态的PD患者行同侧vim/vop核和pvp核联合毁损手术，能全面改善PD患者的症状，是一种安全有效的手术方法。

Microelectrode Guided Thalamotomy and Posteroventral Pallidotomy for Parkinson's Disease 86 Cases

Objective: To observe the outcome ipsilateral thalamotomy (vim/vop) and posteroventral pallidotomy (PVP) for parkinson's disease (PD). Methods: With the hehp of microelectrode guided technique, ipsilateral thalamotomy (vim/vop) and posteroveritral pallidotomy (PVP) were used for 30 parkinson's patients. Results: The outcome was excellent and several typical symptoms were improved: tremor 100%, rigidity 91.3% bradykinesia 87.3%; and “off” state 76. 3%. No permanent operative complica-tions were found. Conclusions: For Parkinsonism patients with tremor rigidity, bradykinesia and “on” and “off” state,the microelectrode-guided ipsilateral vim/vop thalamotomy and posteroventral pallidotomy is a safe and effective surgical therapy,which can alleviate symptoms of PD.