| 黄连软膏处方优化与流变学考察 |
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| 引用本文： | 关志宇,王森,管咏梅,朱卫丰,刘红宁,杨俊免,陈丽华.黄连软膏处方优化与流变学考察[J].中国实验方剂学杂志,2012,18(9):10-13. |
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| 作者姓名： | 关志宇 王森 管咏梅 朱卫丰 刘红宁 杨俊免 陈丽华 |
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| 作者单位： | 江西中医学院,南昌,330004 |
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| 基金项目： | "十一五"国家科技支撑计划(2008BA153B07);江西省自然基金项目(2007GQY2288);江西省卫生厅中医药科研计划(2008A013) |
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| 摘 要： | 目的:优选黄连软膏的基质处方并测定其流变学参数.方法:以外观、稳定常数、冷热破坏等因素的综合评分为考察指标,采用均匀设计法优化黄连软膏处方,并测定流变学参数.结果:优化处方为十八醇12.060 g,单硬脂酸甘油酯10.018 g,聚山梨醇酯-80 7.831 g,山梨醇酐单油酸酯-60 3.173 g,黄连软膏流变学参数(黏度、屈服值、触变性、蠕变等)优良.结论:优选基质处方稳定可行,外观良好,黏度、延展性符合生产与临床应用需要.
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| 关 键 词： | 均匀设计 软膏剂 流变学 |
| 收稿时间： | 2011/11/20 0:00:00 |
Formulation Optimization and Rheology Determination of Huanglian Ointment |
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| GUAN Zhi-yu,WANG Sen,GUAN Yong-mei,ZHU Wei-feng,LIU Hong-ning,YANG Jun-mian and CHEN Li-hua.Formulation Optimization and Rheology Determination of Huanglian Ointment[J].China Journal of Experimental Traditional Medical Formulae,2012,18(9):10-13. |
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| Authors: | GUAN Zhi-yu WANG Sen GUAN Yong-mei ZHU Wei-feng LIU Hong-ning YANG Jun-mian and CHEN Li-hua |
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| Institution: | Jiangxi University of Traditional Chinese Medicine,Nanchang 330004, China;Jiangxi University of Traditional Chinese Medicine,Nanchang 330004, China;Jiangxi University of Traditional Chinese Medicine,Nanchang 330004, China;Jiangxi University of Traditional Chinese Medicine,Nanchang 330004, China;Jiangxi University of Traditional Chinese Medicine,Nanchang 330004, China;Jiangxi University of Traditional Chinese Medicine,Nanchang 330004, China;Jiangxi University of Traditional Chinese Medicine,Nanchang 330004, China |
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| Abstract: | |
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| Keywords: | uniform design ointment rheology |
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