通心络胶囊不同剂量治疗冠心病心绞痛疗效观察

[目的]评价不同剂量通心络胶囊对冠心病心绞痛的疗效。[方法]采用随机双盲对照法,对47例冠心病心绞痛患者分为治疗组24例和对照组23例,分别采用通心络胶囊不同剂量治疗,4周后比较两组临床症状的变化。[结果]中医证候疗效:治疗组和对照组临床痊愈分别为25.0%和26.1%;显效率分别是29.2%和26.1%,无显著性差异;心绞痛疗效:治疗组和对照组显效率分别是58.3%和56.5%,无显著性差异;心电图疗效:治疗组和对照组显效率分别是16.7%和17.4%,不具有显著性差异。[结论]通心络胶囊治疗冠心病心绞痛疗效好,改善中医症状方面有优势。

Clinical Effect of Different Doses of Tongxinluo Capsule on Angina Pectoris in Coronary Heart Disease

(Objective) To evaluate the clinical effect of different doses of Tongxinluo (dredging cardiac collateral) capsule on angina pectoris in coronary heart disease. (Methods) Forty-seven patients with angina pectoris in coronary heart disease were selected and randomly divided into treatment(24 cases, treating with different doses of Tongxinluo capsule) and control group(23 cases). Double-blind and controlled method were adopted to compare the clinical symptom changes four weeks later. (Results) The improvement of TCM syndrome was better in treatment group than that of control group. The recovery and excellence rate of treatment group were individually 25.0% and 29.2%. There were no difference between two groups. Recovery and excellence rate of control group were individually 26.1% and 26.1%. Treating effect on angina pectoris hadn't difference between the treatment group control group. The excellence rates were individually 58.3% and 58.6%. The excellence effect on electrocardiogram in treatment group hadn't any difference with that of control group. They were individually 16.7% and 17.4%. (Conclusions) Tongxinluo capsule has a better curative effect on angina pectoris in coronary heart disease and may improve TCM syndrome.