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The biocompatibility of compressed collagen foam plugs
Authors:Jeffrey D. Robinson  Joseph W. Yedlicka  Mark C. Bildsoe  Zeev Vlodaver  David W. Hunter  Wilfrido Castañeda-Zúñiga  Kurt Amplatz M.D.
Affiliation:(1) Present address: Department of Radiology, University of California Center for the Health Sciences, Los Angeles, California;(2) Present address: Department of Radiology, Hennepin County Medical Center, Minneapolis, Minnesota;(3) Department of Diagnostic Radiology, The University of Minnesota Hospital and Clinic, Room J2-489A, Harvard Street at East River Road, Box 292 UMHC, 55455 Minneapolis, MN, USA
Abstract:The tissue reaction to reexpanded, purified bovine collagen sponge placed percutaneously into the lung, pleural space, liver, kidney, and muscle was studied in dogs and rabbits. In addition, the biocompatibility and radiopacity of tantalumtreated collagen foam plugs was examined. No adverse effects were found. We believe that collagen plugs may be of use in occluding needle tracts from biopsy sites to prevent complications such as bleeding or pneumothoraces.
Keywords:Biocompatibility  Gelfoam plugs  Tantalum  Biopsy  Pneumothorax
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