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糖尿病患者血小板参数、血液流变学和凝血功能指标检测的临床意义
引用本文:李德奎,刘跃,朱名安,黄萍,杜娟.糖尿病患者血小板参数、血液流变学和凝血功能指标检测的临床意义[J].实用诊断与治疗杂志,2008,22(11):801-803.
作者姓名:李德奎  刘跃  朱名安  黄萍  杜娟
作者单位:郧阳医学院附属太和医院检验部,湖北省十堰市,442000
摘    要:目的:探讨糖尿病患者血小板参数、血液流变学和凝血功能指标的临床价值.方法:对46例糖尿病有微血管病变患者、46例糖尿病无微血管病变患者和90例正常对照组的血浆凝血酶原时间、活化部分凝血活酶时间、凝血酶时间、纤维蛋白原进行检测,测定三组人群血流变参数及血小板参数.结果:糖尿病有微血管病变组凝血酶原时间、活化部分凝血活酶时间、凝血酶时间均低于糖尿病无微血管病变组,而纤维蛋白原高于糖尿病无微血管病变组,两者之间差异有统计学意义(P<0.05);血小板参数中平均血小板体积高于糖尿病无微血管病变组(P<0.05),而血小板分布宽度、血小板计数和血小板压积差异均无统计学意义(P>0.05);血流变参数中全血黏度、血浆黏度、红细胞压积均高于糖尿病无微血管病变组.结论:常规检测血小板参数、血液流变学和凝血功能指标,对糖尿病微血管病变患者的病情预测和早期诊治有重要意义.

关 键 词:糖尿病  凝血功能  血小板参数  血液流变学

Clinical significance of determination of the platelet, hemorheology and coagulation parameters in patients with diabetes mellitus
LI Dekui,LIU Yue,ZHU Ming'an,et al..Clinical significance of determination of the platelet, hemorheology and coagulation parameters in patients with diabetes mellitus[J].Journal of Practical Diagnosis and Therapy,2008,22(11):801-803.
Authors:LI Dekui  LIU Yue  ZHU Ming'an  
Institution:LI Dekui,LIU Yue,ZHU Ming'an,et al.Department of Clinical Laboratory,the Affiliated Taihe Hospital of Yunyang Medical College,Shiyan 442000,China
Abstract:Objective To explore the clinical significance of the platelet,hemorheology and coagulation parameters in patients with diabetes mellitus.Methods The levels of PT,APTT and TT,FIB,the platelet parameters and hemorheology in 46 diabetes mellitus patients with microangiopathy and 46 diabetes mellitus patients without microangiopathy and 90 normal controls.Results The levels of PT,APTT and TT in the group of diabetes with microangiopathy were obviously lower than those in the group of diabetes without microangi...
Keywords:Diabetes mellitus  coagulation  platelet parameters  hemorheology  
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